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Tuesday, January 06, 2009

Dharmendra & Jopling's classifications deal with Leprosy

Question 61
Dharmendra & Jopling's classifications deal with
a.       TB
b.      Leprosy
c.       Syphilis
d.      Polio
a.       Leprosy
Park 18th edition Page 256, 257
Behl, 10th Edition Page 224
Old Editions
Ridley-Joplin Classification of leprosy
Depending upon the immunological resistance of persons to Mycobacterium leprae, leprosy can present with different clinical signs. The resistance of individuals varies from very strong to nil, with all possible grades in between.
Thus leprosy can be ecognizeded by high resistance & low number of bacilli (tuberculoid leprosy) or it can be ecognizeded by very low resistance and high number of bacilli (lepromatous leprosy). Between these two ends of the spectrum, there is decrease in resistance and increase in number of bacilli in the body giving rise to borderline tuberculoid, borderline and borderline lepromatous kinds of leprosy. This classification was proposed by Ridley and Joplin.

In addition, an early stage of disease, indeterminate leprosy’ is ecognized that can be self-healing or may develop any of the above-mentioned forms.
Self Explanatory
Dharmendra’s Scale and Ridley’s scale are used for grading of Bacterial Index
Fernandez reaction is delayed-type hypersensitivity reaction to Dharmendra antigen in LEPROSY.

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