Propofol suitable for day care surgery

026. Which of the following intravenous induction agents is the most suitable for day care surgery?

1. Morphine

2. Ketamine

3. Propofol

4. Diazepam

Answer

3. Propofol

Reference

Clinical Anaesthesia 3^rd Edition – Morgan Page 173

Also seen in

KDTripathi,5^th Edition Page 343

Lee, 12^th Edition, Pages 176, 417

SARP - SARP 6^th Edition Page 108

PARAS - PARAS 4^th Edition Page 46

Sure Sucess in PG Entrance 1^st Edition Page 93

Quality

Spotter

Status

Repeat - All India 2003 - See Q.No 3 in RxPG AIPG 2003 Book and Q.No 1 in AIPG 2004 books

QTDF

All books give this

Discussion

Propofol is Di-Isopropylphenol

Ä It is prepared as an emulsion in 10% Soyabean oil and 1.2% egg phosphatide and 2.25%Glycerol

Ä Induction dose is 2-3 mg/kg

Ä Highly lipophilic

Ä 30%-40% of patients complain of pain/burning during injection.

Ä Induction is rapid and recovery of consciousness after 4-7 minutes

Ä Post anaesthetic Performance of Mental, Manual and Mechanical task is back to normal within 1-2 hours

Ä Suited for Day care Surgery

Ä Safe for patients with Acute Intermittent Porphyria

Ä It does not trigger Malignant hyperthermia

Ä Hypotension is a common side effect

Ä Apnoea is common after induction and may last for 40-50 seconds

Ä Antioxidant

Ä Antiemetic

Ä Antipruritic

Explanation

Self Explanatory.

Comments

Ketamine is the anaesthesia of choice for patients in shock and produces delirium and is not the drug for Day Care Anaesthesia. Morphine is used for pain relief and Diazepam for sedation

Tips

This is an Often Repeated Question. Similarly there is a long list of what to use and what not to use in each specific conditions and the fact is that those are asked often and you have no other way than to prepare them. Know the key details about all the anaesthetic agents.