Vitamin K is required for carboxylation of clotting factors..

Question 24

Which Vitamin is required for carboxylation of clotting factors..

a.       Vitamin A

b.      Vitamin D

c.       Vitamin E

d.      Vitamin K

Answer

d) Vitamin K

Reference

Harper 27^th Edition Page : 495

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Discussion

Vitamin K (K from "Koagulation" in German) denotes a group of lipophilic (fat-soluble), and hydrophobic, vitamins that are needed for the posttranslational modification of certain proteins, mostly required for blood coagulation. Chemically they are 2-methyl-1,4-naphthoquinone derivatives.

Vitamin K₂ (menaquinone, menatetrenone) is normally produced by bacteria in the intestines, and dietary deficiency is extremely rare unless the intestines are heavily damaged or are unable to absorb the molecule

Explanation

Self Explanatory

Vitamin K is required for Synthesis of Blood Clotting Proteins. Vitamin K is the Co Enzyme for carboxylation of Glutamate in Post Synthetic Modification of Calcium Binding Proteins.

Comments

Ä     Vitamin K is also important in synthesis of Bone Calcium Binding Proteins

Ä     The recommended Daily Allowance is 120 microgram

Tips

There is an unrelated drug sometimes referred to in slang as vitamin K. It is Ketamine