Cushing’s disease presents with

Question 86

Cushing’s disease presents with

a.       Increased ACTH, Increased Cortisol

b.      Decreased ACTH and Decreased Cortisol

c.       Increased ACTH and Decreased Cortisol

d.      Increased Catecholamines

Answer

a. Increased ACTH and Increased Cortisol

Reference

Harrison 16^th Edition Page 2135

QTDF

Harrison

Quality

Reader

Status

New

Discussion

Cushing's syndrome (also called hypercortisolism or hyperadrenocorticism) is an endocrine disorder caused by high levels of cortisol in the blood from a variety of causes, including primary pituitary adenoma (known as Cushing's disease), primary adrenal hyperplasia or neoplasia, ectopic ACTH production (e.g., from a small cell lung cancer), and iatrogenic (steroid use).

Explanation
Self Explanatory

Comments

Cushing's disease was described by American physician, surgeon and endocrinologist Harvey Cushing (1869-1939) and reported by him in 1932.

Tips

Question about the earliest manifestation of Cushings was asked in 2004