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Monday, December 15, 2008

Proteins are sorted by Golgi bodies

Question 33
Proteins are sorted by
a.       Golgi Bodies
b.      Mitochondria
c.       Ribosomes
d.      Nuclear Membranse
a. Golgi bodies
Harper 27th Edition Page 506
Most Book
Proteins must travel from polyribosomes top many different sites in the cell to perform their particular functions. Some are destined to be components of specific organelles, others for the cytosol or for export and yet other will be located in the various cellular membranes. Thus there is considerable intracellular traffic of proteins. Many studies have shown that the Golgi apparatus plays a major role in sorting of proteins for their correct destination.
Self Explanatory
The entire pathway of ERà Golfi apparatus à Plasma membrane is often called the secretory or exocytotic pathway. Secretory pathway involving transport vesicles is called “constitutive”
Other proteins destined for secretion are carried in secretory vesicles. These are prominent in pancreas and certain other glands. Their mobilization and discharge are regulated and often referred to as “regulated secretion”

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