TNPG 2005 BIOCHEMISTRY & BIOPHYSICS

BIOCHEMISTRY & BIOPHYSICS

1) Vitamin useful in the treatment of Hartnup’s disease is

a. Biotin

b. Niacin

c. Folic Acid

d. Thiamine

Answer : b) Niacin

Reference: Harrison 15^th Edition Chapter 353

2) Ketogenic amino acid

a. Leucine

b. Valine

c. Alanine

d. Tryptophan

Answer : Leucine

Reference: harper 24^th Edition Page 310

3) Maple Syrup Urine Disease is due to defect in the metabolism of

a. Unbranched aminoacid

b. Phenyl alanine

c. Branched Chain Amino Acid

d. Tyrosine

Answer : c) Branched Chain Amino Acid

Reference: Chaterjee 6^th Edition Page 456

4) Why muscle glycogen is not useful in elevation of Glucose level of blood because muscle does not contain

a. Glucose – 6 – phosphatase

b. Phosphorylase

c. Cyclic AMP

d. Protein Kinase

Answer : a) Glucose – 6 – phosphatase

Reference: Chaterjee 6^th Edition Page 291

5) Irreversible enzyme step all except –

a. phosphofructokinase

b. Phosphohexose isomerase

c. hexokinase

d. Pyruvate kinase

Answer : B) Phosphohexose isomerase

Reference: Chaterjee 6^th Edition Page 306

6) NADPH not produced for fatty acid synthesis from

a. HMP shunt

b. malic enzyme

c. lactic dehydrogenase

d. isocitrate dehydrogenase

Answer : c) lactic dehydrogenase

Reference: Chaterjee 6^th Edition Page 355

7) The main role of Vitamin K is

a. Carboxylation

b. Formatiuon of active succinate

c. Heme systhessis

d. Synthesis of Fatty acid

Answer : a) Carboxylation

Reference: Chaterjee 6^th Edition Page 155

8) Enterohepatic circulation of bile salt is affected and that leads to

a. Vitamin K deficiency

b. Hypertension

c. Hemolytic anemia

d. Diabetes Insipidus

Answer : a) Hemolytic Anemia

Reference: Chaterjee 6^th Edition Page 155

9) Bile salts is produced from

a. Cholesterol

b. Amino acids

c. Glycogen

d. Lecithin

Answer : a) Cholesterol

Reference: Ganong 22^nd Edition Page 501

10) Vitamin K deficiency occurs in

a. Obstructive Jaundice

b. Hemolytic Jaundice

c. Prehepatic Jaundice

d. Secondaries liver

Answer : a) Obstructive Jaundice

Reference: Chaterjee 6^th Edition Page 155

11) Antiracchitic Vitamin D is activated in the following organ

a. Muscle

b. Lungs

c. Kidney

d. Intestine

Answer : c) Kidney

Reference: Ganong 22^nd Edition Page 388

12) Urea synthesized mainly in

a. Liver

b. Heart

c. Kidney

d. brain

Answer : Liver

Reference: Chaterjee 6^th Edition Page 411

13) The End product of purine metabolism is

a. Urea

b. Creatinine

c. Uric Acid

d. GLycine

Answer : c) Uric Acid

Reference: Chaterjee 6^th Edition Page 212

14) Folic acid antagonist for Cancer is

a. Methotrxate

b. Vincristine

c. Cyclosporine

d. Azathioprine

Answer : a) Methotraxate

Reference: Tripathi 5^th Edition Page 772

15) In Galactosemia the Cataract is due to the production of

a. Sorbital

b. Galactose

c. Glucose

d. Galactositol

Answer : d) Galactositol

Reference: Chaterjee 6^th Edition Page 312

16) Following are causes of Vitamin B 12 deficiency except

a. Strict vegetarian

b. Blind loop Syndrome

c. Diphyllobothrium latum infection

d. Chronic Blood loss

Answer :D) Chronic Blood Loss

Reference: Chaterjee 6^th Edition Page 182

17) Hyaluronic acid is made up of

a. N-Acetyl Glusosamine

b. D- GLucuronic Acid

c. Both

d. None

Answer : C) Both

Reference: Chaterjee 6^th Edition Page 38

18) Fluoride inhibits

a. enolase

b. Glukokinase

c. Aldolase

d. Phosphofructokinase

Answer : a) Enolase

Reference: harper 24^th Edition Page 178

19) Thiamine rich in

a. Unpolished rice

b. Fish

c. Soyabean

d. All of these

Answer : a) Unpolished rice

Reference: Chaterjee 6^th Edition Page 159

20) The initial change seen in Hyperventilation regarding PCO₂ is

a. No changes

b. Increased PCO₂ with increased pH

c. Normal PCO₂ with increased pH

d. Decreased PCO₂ with increased pH

Answer : d) Decreased PCO2 with increased pH

Reference: Chaterjee 6^th Edition Page

21) Characteristics of Insulin resistant syndrome all except

a. Hypoglycemia

b. May be associated with PCOD

c. Obesity

d. Hyperglycemia

Answer : Hypoglycemia

Reference: Harrison 15^th Edition Chapter 77

22) FSH and LH are Produced by

a. Anterior pituitary

b. Hypothalamus

c. Placenta

d. Ovary

Answer : A) Anterior Pituitary

Reference: Ganong 22^nd Edition Page 397

23) True about Heparin is

a. Basic in nature

b. Contains Glucronic Acid

c. LMW Heparin selectively inhibit Xa

d. no effect on platelet

Answer : c) LMW Heparin selectively inhibit Xa

Reference: Chaterjee 6^th Edition Page 39

24) About PGE₂

a. Synthesized in fetus

b. Closes the ductus arteriosus

c. Both

d. None

Answer : b) Closes the ductus arteriosu

Reference: Tripathi 5^th Edition Page 159